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Heteroaromatic Lipoxin A4 Analogues formatIsbn:Hardcover - 9783642246319 Presley scored NrIn this thesis Colm Duffy reviews the chemistry and biology of stable lipoxin analogues. Colm has prepared for the first time ever a pyridine containing LXA4 analogue in enantiomerically pure form. Biological evaluation determined that both epimers at the benzylic position suppress key cytokines known to be involved in inflammatory disease, with the (R) epimer proving most efficacious. Moreover the author developed an excellent route to a related
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